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English to Tagalog: Study Drug (Portions) General field: Medical Detailed field: Medical: Pharmaceuticals
Source text - English Dosage and administration
Adults
Treatment of essential hypertension
The recommended dose is 40 mg once daily. Some patients may already benefit at a daily dose of 20 mg. In cases where the target blood pressure is not achieved, telmisartan dose can be increased to a maximum of 80 mg once daily. Alternatively, telmisartan may be used in combination with thiazide-type diuretics such as hydrochlorothiazide, which has been shown to have an addictive blood pressure lowering effect with telmisartan. When considering raising the dose, it must be borne in mind that the maximum antihypertensive effect is generally attained four- eight weeks after the start of treatment.
In patients with severe hypertension treatment with telmisartan at doses up to 160 mg alone and in combination with hydrochlorothiazide 12.5-25 mg daily was well tolerated and effective
Prevention of cardiovascular morbidity and mortality
The recommended dose is 80 mg once daily. It is not known whether doses lower than 80 mg of telmisartan are effective in preventing cardiovascular morbidity and mortality
When initiating telmisartan therapy for the prevention of cardiovascular morbidity and mortality, monitoring of blood pressure is recommended, and if appropriate adjustment of medications that lower blood pressure may be necessary.
Telmisartan (MICARDIS) may be taken with or without food
Renal Impairment
No posology adjustment is required for patients with renal impairment, including those on haemodialysis.
Telmisartan is not removed from blood by hemofiltration
Hepatic impairment
In patients with mild to moderate hepatic impairment the posology should not exceed 40 mg once daily
Translation - Tagalog Dosis at pagbibigay
Mga nasa wastong gulang
Paggamot sa esensiyal na mataas na presyon ng dugo
Ang rekomendadong dosis ay 40 mg minsan isang araw. Ang ilang pasyente ay maaaring makinabang na sa arawang dosis na 20mg. Sa mga kaso kung saan ang target na presyon ng dugo ay hindi nakamit, maaaring taasan ang dosis ng telmisartan sa maksimum na 80 mg minsan isang araw. Halinhinan, maaaring gamitin ang telmisartan kasama ng thiazide-type na pampaihi (diuretics) tulad ng hydrochlorothiazide, na naipakita nang may paulit-ulit na pampababang epekto sa presyon ng dugo kasama ang telmisartan. Kapag pinag-iisipang itaas ang dosis, dapat isipin na ang maksimum na epektong pampababa ng presyon ng dugo ay nakukuha pangkalahatan sa apat hanggang walong linggo pagkatapos simulan ang gamutan.
Sa mga pasyenteng ginagamot ng telmisartan sa malubhang pagtaas ng presyon ng dugo sa dosis na hanggang 160 mg lamang at kasama ng hydrochlorothiazide ang 12.5-25 mg araw-araw ay nakayanang mabuti at epektibo
Pagpigil sa cardiovascular na estado ng pagkakasakit at pagkamatay
Ang rekomendadong dosis ay 80 mg minsan isang araw. Hindi alam kung ang mga dosis na mas mababa sa 80 mg ng telmisartan ay epektibo sa pagpigil ng cardiovascular na estado ng pagkakasakit ag pagkamatay. Kapag sinisimulan ang gamutan sa telmisartan para sa pagpigil ng cardiovascular na estado ng pagkakasakit at pagkamatay, ang pagmonitor sa presyon ng dugo ay inirerekomenda, at kung ang akmang pagwasto sa mga medikasyong nagpapababa sa presyon ng dugo ay maaaring kailangan.
Ang telmisartan (MICARDIS) ay maaaring inumin nang may pagkain o wala.
Pagkasira ng bato
Walang pagwawasto sa pag-aaral ng dosis ng gamot na kailangan para sa mga pasyenteng may pagkasira ng bato, kasama ang mga nasa haemodialysis.
Ang telmisartan ay hindi naaalis sa dugo sa pamamagitan ng hemofiltration.
Pagkasira ng atay
Sa mga pasyenteng may banayad hanggang katamtamang pagkasira ng atay ang pag-aaral sa dosis ng gamot ay hindi dapat humigit sa 40 mg minsan isang araw
English to Tagalog: Antifungal drug General field: Medical Detailed field: Medical: Pharmaceuticals
Source text - English (Drug) has several characteristics that provide additional benefits over voriconazole, the current standard of care for invasive aspergillosis and mucormycosis. A key advantage of (drug) over voriconazole is its breadth of antifungal activity, which makes it a more versatile option, particularly before confirmation of causative pathogen. Importantly, (drug) is active against Mucorales fungi, while voriconazole is not. This offers two key benefits. Firstly, since aspergillosis and mucormycosis can be difficult to distinguish, the use of (drug) provides physicians with the confidence that their aspergillosis patients are receiving appropriate coverage when Mucorales co-infection cannot be ruled out. Secondly, overuse of voriconazole has been linked with breakthrough mucormycosis; consequently, aspergillosis treatments with activity against Mucorales may help to reduce the risk of this type of incident. Thus, (drug) is a reliable treatment choice when Aspergillus and/or Mucorales infection is suspected.
Name of drug has to be cited as (drug) as per confidentiality agreement
Translation - Tagalog Ang (drug) ay may ilang katangiang nagbibigay ng dagdag na mga benepisyo kesa voriconazole, ang kasalukuyang pamantayan ng pangangalaga para sa invasive aspergillosis at mucormycosis. Isang pangunahing kalamangan ng (drug) sa voriconazole ay ang lawak ng antifungal na aktibidad nito, na gumagawa ritong isang opsiyon na mas maraming kakayahan, partikular bago ang kumpirmasyon ng sanhing sakit (causative pathogen). Mahalaga, ang (drug) ay aktibo laban sa Mucorales fungi, habang ang voriconazole ay hindi. Nag-aalok ito ng dalawang pangunahing benepisyo. Una, dahil ang aspergillosis at mucormycosis ay puwedeng mahirap kilalanin, ang paggamit ng (drug) ay nagbibigay sa mga doktor ng tiwala na ang kanilang mga pasyente ng aspergillosis ay tumatanggap ng akmang paggamot kung hindi maisantabi ang kasabay na impeksiyon ng Mucorales. Ikalawa, ang sobrang paggamit ng voriconazole ay naikawing na sa pasimunong mucormycosis; dulot nito, ang mga paggamot sa aspergillosis na may aktibidad laban sa Mucorales ay maaaring makabawas sa panganib ng uri ng insidenteng ito. Kaya ang (drug) ay maaasahang pagpili sa paggamot kung hinihinala ang impeksiyon ng Aspergillus at/o Mucorales.
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Translation education
Master's degree - University of the Philippines
Experience
Years of experience: 34. Registered at ProZ.com: Aug 2010.
Writer, editor, researcher, and translator, Ariel N. Valerio graduated from the University of the Philippines in Diliman with a bachelor's degree in Philippines Studies. He served as editor of the UP Writers Club's "The Literary Apprentice" and the UP student publication "The Philippine Collegian" while an undergraduate student. He worked afterward with the Sentro ng Wikang Filipino -- UP System as University Researcher, writing and editing for the magazine "Daluyan" and other publications. He also served as faculty member of the Department of Filipino and Philippine Literature from 1990-2000. He worked with the UP System Information Office as managing editor of "Forum" and the AMA Computer University as Training Director. He concentrated on translation jobs starting 2005.
Keywords: health care, medical, clinical trials, clinical studies, research study, translation, english, tagalog, literature, brochure. See more.health care, medical, clinical trials, clinical studies, research study, translation, english, tagalog, literature, brochure, pamphlet, books. See less.
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