tissue homing
Russian translation: см.
| 21:47 Jul 21, 2017 |
| English to Russian translations [PRO] Medical - Medical: Pharmaceuticals | |||||||
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|  Selected response from: Margarita Vidkovskaia Russian Federation Local time: 09:51 | ||||||
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| 4 +1 | см. |
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| 4 | тканевый хоминг |
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Answers
28 mins confidence: 
тканевый хоминг Explanation: Как здесь (не взыщите за ссылку, но я думаю термин вверен): http://a2ch.ru/2013/01/13/davno-ne-bylo-otvechaiu-na-vashi-v... имеется в виду хоминг клеток в определенные ткани (в данном случае, видимо, в периферическую лимфоидную ткань) |
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11 hrs confidence: peer agreement (net): +1
peer agreement (net): +1см. Explanation: Препарат PCI-32765, ингибитор тирозинкиназы Брутона, препятствует выживанию клеток [лимфоцитов] и их избирательному/специфическому возвращению [из кровотока] в ткани [лимфоидных органов] in vitro и in vivo при хронической лимфоцитарной лейкемиии. Lymphocyte homing refers to adhesion of the circulating lymphocytes in blood to specialized endothelial cells within lymphoid organs, facilitated by diverse tissue-specific adhesion molecules on lymphocytes (homing receptors) and on endothelial cells (vascular addressins). Free lymphocytes constantly recirculate in blood after their re-entry from lymphoid tissue, via lymphatic and thoracic ducts. This happens so that the full repertoire of antigenic specificities of lymphocytes is continuously represented throughout the body. Homing happens in tissue-specific manner—e.g. B lymphocytes migrate better to mucosa-associated lymphoid tissue (Peyer's patches), and T lymphocytes preferentially to the peripheral lymph nodes.[2] https://en.wikipedia.org/wiki/Lymphocyte_homing_receptor Lymphocyte homing and homeostasis https://www.ncbi.nlm.nih.gov/pubmed/8600538 |
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